Multiple choice

As a general rule, the DNA of most organisms is negatively supercoiled. Which of the following DNA replication enzymes regulates the negative supercoiling of the DNA molecule?

  1. Helicases

  2. DNA polymerases

  3. Topoisomerases

  4. DNA clamp

  5. DNA gyrase

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

DNA gyrase relieves strain while double-strand DNA is being unwound by helicase. This causes negative supercoiling of the DNA.