Multiple choice Among the following, ___________ is a semi-synthetic opioid drug. Sufentanil Buprenorphine Butorphanol Heroin Reveal answer Fill a bubble to check yourself D Correct answer Explanation Heroin is a semi-synthetic opioid drug synthesized from morphine, a derivative of the opium poppy. It is the 3,6-diacetyl ester of morphine (di-acetyl-morphine) and a morphine prodrug.