Multiple choice

Which of the following increases oxygen binding with hemoglobin?

  1. Increase in oxygen concentration

  2. Increase in CO2 concentration

  3. Decrease in oxygen concentration

  4. Increase in B.P.G concentration
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A Correct answer
Explanation

Increased oxygen concentration shifts the oxygen-hemoglobin dissociation curve to the left, increasing hemoglobin's affinity for oxygen (more O2 binds at a given partial pressure). Conversely, increased CO2 or BPG (2,3-bisphosphoglycerate) decreases oxygen binding by shifting the curve to the right (Bohr effect).

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