Multiple choice

What is hybridisation of nucleic acids?

  1. The pairing of radioactively labelled RNA or DNA with the complementary strand of denatured DNA

  2. Pairing of RNA with complementary denatured DNA

  3. Pairing of radioactively labelled DNA with denatured DNA

  4. Options (1), (2) and (3) are true

  5. Pairing of chromosomes
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

A strand of radioactively labelled RNA or DNA, when added to a denatured DNA preparation will act as a probe for DNA molecules to which it is complementary. This hybridisation of complementary strands of nucleic acid is very useful for isolating a specific fragment of DNA from a complex mixture. Hence, this option is the correct answer.

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