Multiple choice

Which among the following genetic diseases is not inherited?

  1. 47, XYY

  2. 47, XX, +21

  3. 47, XXY

  4. 45, X

  5. 1p36 deletion syndrome
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A Correct answer
Explanation

47, XYY is not inherited but usually occurs as a random event during the formation of sperm cells. An incident in chromosome separation during anaphase II (of meiosis II) called nondisjunction can result in sperm cells with an extra copy of the Y-chromosome. If one of these atypical sperm cells contributes to the genetic makeup of a child, the child will have an extra Y-chromosome in each of the body's cells.

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