Multiple choice

Which among the following is an autosomal recessive metabolic genetic disorder?

  1. Sickle-cell disease

  2. Cystic fibrosis

  3. Tay-Sachs disease

  4. Phenylketonuria

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Phenylketonuria (PKU) is an autosomal recessive metabolic genetic disorder characterized by an error in the genetic code for the hepatic enzyme phenylalanine hydroxylase (PAH), rendering it nonfunctional.This enzyme is necessary to metabolize the amino acid phenylalanine (Phe) to the amino acid tyrosine.