Multiple choice

Human immunodeficiency virus (HIV) presents a complex knot for scientists to unravel. Which of the following is a coreceptor for HIV?

  1. CD8

  2. CD54

  3. CR5

  4. CXCR4

  5. RANTES

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

CXCR4 is a chemokine receptor which HIV utilizes as a coreceptor for entry into naive CD4+ T-cells and mature dendritic cells. Another chemokine receptor, CCR5, is used particularly for entry of HIV into immature dendritic cells, macrophages and activated effector or memory CD4+ T-cells.