Multiple choice

The human immunodeficiency virus (HIV) interacts with which of the following cell-surface molecules to gain entry into cells of the immune system?

  1. CD4

  2. CD19

  3. CD40 ligand

  4. CD8

  5. CD25
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A Correct answer
Explanation

This is a major portal of entry, though not the only one. The chemokine receptors CXCR4 and CCR5 are also major portals of entry and reduce the CD4 positive helper T cell numbers dramatically (see Case 3.11 Acquired immune deficiency syndrome: Kaposi's sarcoma

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