Multiple choice

Which of the following statements regarding TCA is incorrect?

  1. The major eventual substrate of the cycle is ADP.

  2. The regulation of TCA cycle is largely determined by product inhibition and substrate availability.

  3. For each acetyl group that enters the citric acid cycle, three molecules of NADH are produced.

  4. The citrate goes through a series of chemical transformations, losing two carboxyl groups as HCO3-.

  5. In TCA, citrate is used for feedback inhibition.
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

The citrate goes through a series of chemical transformations, losing two carboxyl groups as CO2. The carbons donated by acetyl-CoA become a part of the oxaloacetate carbon backbone after the first turn of the citric acid cycle.

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