Multiple choice

Retroviruses are used for inserting a normal gene into the genome to replace an abnormal disease causing gene in gene therapy of

  1. ADA-SCID
  2. α1-antitrypsin deficiency
  3. Mucoviscidosis
  4. Christmas disease
  5. Rheumatoid arthritis

  1. Only 1 and 2

  2. Only 1, 4 and 5

  3. Only 2, 3 and 4

  4. Only 3 and 4

  5. Only 3, 4 and 5
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

First viruses to be used as vectors in gene therapy experiments were retroviruses.
Retroviruses are used for inserting a normal gene into the genome to replace an abnormal disease causing gene. In gene therapy of ADA-SCID or ADA deficiency, haemophilia b, rheumatoid arthritis, etc.

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