Multiple choice

The inserted gene may damage the function of one of the host's genes. Which among the following insertion causes loss of protein function in host genes?

  1. Insertion between promoter and upstream enhancers

  2. Insertion in a translated region

  3. Insertion in an intron

  4. Insertion in 5' untranslated region

  5. Insertion in promoter

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Insertion in an intron altered splicing pattern/splicing failure. It usually results in protein truncation or the production of inactive mis-spliced products, although more complex effects are common.