Multiple choice

Latency associated nuclear antigen (LANA) is present in primary effusion lymphoma cells that react with antibodies from patients with Kaposi Sarcoma. A biopsy sample tested positive for LANA by histobiochemistry confirms the presence of

  1. HSV-1 virus

  2. HSV-8 virus

  3. HSV-7 virus

  4. HSV-6 virus

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

A positive test for latency-associated nuclear antigen (LANA-1) confirms the presence of HSV-8 virus. Human herpesvirus 8 (HHV-8) has been identified as the etiological agent of Kaposi’s sarcoma. It expresses high levels of LANA.