Multiple choice

Which among the following cardiovascular defects is accompanied by action potentials of extended duration and flattened oscillations of intracellular calcium ions?

  1. Diastolic dysfunction

  2. Arrhythmogenic right ventricular cardiomyopathy

  3. Dilative cardiomyopathy

  4. Restrictive cardiomyopathy

  5. Hypertrophic cardiomyopathy

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A Correct answer
Explanation

Dysfunction is accompanied by action potentials of extended duration and flattened oscillations of intracellular Ca2+. During systole, the spike in cytosolic Ca2+ concentration is muted, capping power, while during diastole, it takes too long to pump the Ca2+ back into the sarcoplasmic reticulum, interfering with proper relaxation.