Multiple choice

A patient is suffering from a disorder where adenylate cyclase is non-functional resulting in decreased cAMP levels.

Why is the cAMP infusion not the remedy for the problem?

  1. There was no tissue specificity.

  2. Signalling was not proper.

  3. PKC cannot be activated.

  4. All are true.
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A Correct answer
Explanation

cAMP is the hydrophilic molecule which cannot transverse the plasma membrane easily. To overcome the permeability, more hydrophobic derivatives are used resulting that there was no tissue specificity and all cells increased cAMP level. As a result, non-specific and massive responses are formed.

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