Multiple choice

Which one of the following is an inhibitor of FO portion of ATP synthase?

  1. Fluoro-aluminate

  2. Azide

  3. Tentoxin

  4. DCCD

  5. Efrapeptin
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

DCCD is an inhibitor of FO portion of ATP synthase. DCCD stands for Dicyclohexylcarbodiimide is an organic molecule by which protonated carboxyl groups can be covalently modified. DCCD, when combined with ATP synthase, reacts with carboxyl group of residual amino acid of subunit c at pH greater than 8 and hence, protonated at such high pH.

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