Multiple choice

Which one of the following is an inhibitor of oxidative phosphorylation?

  1. Fluroacetate

  2. Arsenite

  3. Malonate

  4. Piercidin A

  5. Fluoride
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Piercidin A inhibits NADH-CoQ reductase (Complex I) to block electron flow from the latter to CoQ. So oxidations of substrates such as pyruvate, isocitrate, α-ketogluterate, malate and 3-hudroxybutyrate, whose electrons enter the respiratory chain through complex I are prevented.

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