Multiple choice Which is the source of all the germ layers in the embryo? The hypoblast The epiblast Both hypoblast and epiblast Osteoblast Osteoclast Reveal answer Fill a bubble to check yourself B Correct answer Explanation The first epiblast cell moves inward and displaces the hypoblast to create endoderm. Once endoderm is formed, inwardly moving epiblast forms mesoderm. Cells remaining in the epiblast form ectoderm. Thus, the epiblast is source of all germ layers.