Multiple choice general knowledge science & technology

Proteins generated in the __________ are loaded in the cleft of MHC class I molecules

  1. Mitochondria

  2. Endoplasmic reticulum

  3. Cytosol

  4. Lysosyme
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

MHC class I molecules present peptides from endogenous proteins synthesized in the cytosol. These proteins are degraded by the proteasome, transported into the endoplasmic reticulum via TAP, and loaded onto MHC class I molecules. The mitochondria and lysosome are not involved in this pathway.

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