Multiple choice

Which of the following are yielded in a citric acid cycle?

  1. 3 NADH and 2 CO2

  2. 6 NADH and 2 CO2

  3. 6 NADH and 4 CO2

  4. 2 NADH and 4 CO2

  5. 2 NADH and 2 CO2
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A Correct answer
Explanation

NADH is yielded in three steps- (a) oxidation of isocitrate to oxalosuccinate (b) oxidation of α-ketogluterate to succinyl CoA and (c) oxidation of malate to oxaloacetate. Thus, 3 NADH molecules are formed and CO2 is produced during conversion of oxalosuccinate to α-ketogluterate and the latter to succinyl CoA. So in 1 cycle 3 NADH and 2 CO2 are formed.

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