Multiple choice

T cell antigen receptors are distinguished from antibodies by which of the following characterstics?

  1. T cell receptors are glycosylated.

  2. T cell receptors must interact with antigen uniquely presented by other cells but not with free antigen.

  3. T cell receptors bind various cytokines.

  4. T cell receptors bind complement to lyse cells.

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

T cell receptors (TCRs) recognize antigen only when presented by MHC molecules on antigen-presenting cells. Unlike antibodies, TCRs cannot bind free antigen. Options A, C, D are incorrect: TCRs are membrane proteins (not defined by glycosylation), they don't bind cytokines directly, and complement binding is not their function.