Multiple choice

Which of the following statements is not true for chaperonin?

Chaperons are heat shock proteins, which facilitate the interactions on the polypeptide surface to finally give the specifc conformation of proteins. They are categorised into two major groups; Hsp70 system and chaperonine system.

  1. This system contains 60 KDa Hsp.

  2. This system contains 10 KDa Hsp.

  3. It works in association with Hsp 70 system.

  4. It is an oligomeric assembly into which the folded proteins are inserted.

  5. It binds individually to the substrate and helps in the correct formation of protein folding.

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

It is true for Hsp 70 system but not for chaperonin. Chaperonin is an oligomeric assembly, which forms a structure into which the folded protein is inserted. This system mainly has Hsp 60 and Hsp10 and is required at later part of the protein folding process and often work in association with Hsp 70 system.