Multiple choice

If a sudden mutation occurs to the gene responsible for coding DNA polymerase α in a unicellular organism, which function will be stopped in that cell?

In eukaryotic replication,  5 different kinds of polymerases have been demonstrated. They perform different functions.

  1. Initiation of leading strand synthesis

  2. Initiation of replication in both leading and lagging strands

  3. Mitochondrial replication

  4. DNA proof reading in lagging strand

  5. Lagging strand synthesis

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Initiation of replication in both leading and lagging strands. As DNA polymerase α is responsible for synthesis of RNA primer on both the strands, initiation of replication is stopped in both leading and lagging strands. RNA primer provides free –OH at the 3’ end for the attachment of deoxyribonucleotides on both the strands and if it is unable to form, then replication will be stopped.