Multiple choice

How does chloramphenicol affect bacterial translation?

Different antibiotics affect translation in various ways. Some of them prevent ribosomal association with mRNA or block amino acid binding sites on the ribosome to cause damage in the process of translation.

  1. Chloramphenicol causes misreading of the genetic code.

  2. Chloramphenicol inhibits translocation of mRNA along ribosome.

  3. Chloramphenicol blocks peptidyl transferase and formation of peptide bond on the 50S ribosomal subunit.

  4. Chloramphenicol blocks A-site of 50S subunit.

  5. Chloramphenicol inhibits interaction with tRNA and mRNA.
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

It is an antibiotic, which causes inhibition of bacterial translation process by blocking synthesis of peptide bond.

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