Multiple choice

Wobble hypothesis was proposed by F.H.C.Crick (1966) from the structure of anticodon loop in tRNA. Which one of the following is established by this hypothesis?

  1. Economy in tRNA molecules

  2. Initiation of peptide chain

  3. Termination of peptide chain

  4. Elongation of peptide chain

  5. Non-ambiguous nature of genetic code
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A Correct answer
Explanation

A single tRNA type is able to recognise two or more codons by their anticodon loops differing only in the third base, which is known as Wobble position. This kind of Wobbling allows economy of the number of tRNA molecules because several codons meant for the same amino acid are recognised by the same tRNA.

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