Erythroblastosis fatalis can be prevented if the mother is injected at parturition, with an antibody called ___________.
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blocking antibody
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Rh (D) immunoglobulins
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antilymphocyte globulin
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antilymphocyte serum
B
Correct answer
Explanation
Erythroblastosis fetalis is an hemolytic disease of the newborn. It classically results from Rh incompatibility when Rh negative mother carries a foetus, which is Rh positive. Such Rh positive RBC of foetus when comes in contact with the blood of mother, it stimulates maternal antibody production against Rh antigens. The first pregnancy may be normal, but in subsequent pregnancy, these antibodies lyse foetal RBC causing anaemia and even death. However, maternal sensitization and antibody production can be prevented by injecting mother with Rh (D) immunoglobulin at parturition.