Multiple choice

Retroviruses are used for inserting a normal gene into the genome to replace an abnormal disease-causing gene in gene therapy of

  1. ADA deficiency
  2. Alpha-1-antitrypsin deficiency
  3. Cystic fibrosis
  4. Haemophilia b
  5. Rheumatoid arthritis

  1. 1 and 2

  2. 1, 4 and 5

  3. 2, 3 and 4

  4. 3 and 4

  5. 3, 4 and 5
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Correct answer. First viruses to be used as vectors in gene therapy experiments were retroviruses. Retroviruses are used for inserting a normal gene into the genome to replace an abnormal disease-causing gene in gene therapy of ADA deficiency, haemophilia b, rheumatoid arthritis etc.

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