Multiple choice Loss of a purine base to form an apurinic site results into spontaneous mutation by deamination spontaneous mutation by depurination induced mutation errors introduced during DNA repair Reveal answer Fill a bubble to check yourself B Correct answer Explanation Loss of a purine base (A or G) to form an apurinic site (AP site) is depurination, which results into spontaneous mutation. AP site has neither a purine nor a pyrimidine base, either spontaneously or due to DNA damage.