Multiple choice

Which among the following is caused by microdeletion of chromosome 22q11.2?

  1. Velo-cardio-facial syndrome

  2. Fragile X syndrome

  3. Rett syndrome

  4. Bloom syndrome

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A Correct answer
Explanation

It is a chromosomal disorder and is caused by microdeletion of chromosome 22q11.2. It is not visible cytogenetically, but detectable by FISH or comparative genomic hybridization.