Multiple choice

Mutation in the RET oncogene is associated with increased risk of

  1. PNET cancers

  2. Endometrial cancer

  3. Prostate cancer

  4. Adenocarcinoma

  5. Medullary thyroid cancer
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D Correct answer
Explanation

Adenocarcinoma is a cancer arising from the mucosa of the rectum. Cancer cells can also spread from the rectum to the lymph nodes on their way to other parts of the body. RET mutation is responsible for adenocarcinoma RET mutation is responsible for increased risk of medullary thyroid cancer, as well as multiple endocrine neoplasia 2, in which pheochromocytoma and parathyroid adenoma also occur.

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