Multiple choice

Which of the following statements about teixobactin is true?

  1. It is widely used against Gram-positive bacteria.

  2. Mycobacteria soon develops resistance to this antibiotic.

  3. It inhibits cell wall synthesis by binding to lipid II molecule.

  4. It inhibits isoprenyl pyrophosphate, a molecule that carries the building blocks of the peptidoglycan bacterial cell wall.

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

This is the correct answer. Teixobactin is an inhibitor of cell wall synthesis that acts primarily by binding to lipid II, a fatty molecule which is a precursor to peptidoglycan. Binding of teixobactin to lipid precursors inhibits production of the peptidoglycan layer, leading to lysis of vulnerable bacteria.