Acupuncture's pain-relieving effects are mediated by the release of endorphins - the body's natural painkillers. Research shows that naloxone (an endorphin antagonist) can block acupuncture's analgesic effects, supporting this mechanism. Sensory adaptation (A) refers to diminished sensitivity to constant stimuli. Physiological nystagmus (B) is involuntary eye movement. Perceptual defense (C) involves delayed recognition of threatening stimuli.