Multiple choice

Adenosine deaminase(ADA) deficiency is a syndrome that is seen in children especially below 12 years. Which of the following can be considered as a permanent cure to this disorder?

  1. Bone marrow transplantation

  2. Enzyme replacement therapy

  3. Infusion of genetically engineered lymphocytes

  4. Introduction of gene isolated from bone marrow cells producing ADA into cells at early embryonic stages
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D Correct answer
Explanation

Adenosine deaminase deficiency also known as ADA deficiency or ADA-SCID  is an autosomal recessive metabolic disorder that causes immunodeficiency. Introduction of gene isolated from bone marrow cells producing ADA into cells at early embryonic stages can be considered as a permanent cure to this disorder.

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