ISO 9241 defines usability as:
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Extent to which a product can be used by specified users to achieve specified goals with effectiveness, efficiency and satisfaction in a specified context of use.
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The science of designing a website or application that can be easily used by the user and look pleasant to the eyes.
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Methodology of designing more usable product that can help customer to make more profit.
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The science of making technology accessible for physically/ cognitively challenged users.
ISO 9241-11 defines usability as the extent to which specified users can achieve specified goals effectively, efficiently, and with satisfaction in a specified context. Options B, C, and D describe related concepts but are not the ISO definition.
This is the verbatim ISO 9241-11 definition of usability: 'the extent to which a product can be used by specified users to achieve specified goals with effectiveness, efficiency and satisfaction in a specified context of use.' It's a formal, measurable standard covering three dimensions (effectiveness, efficiency, satisfaction) tied to specific users/goals/context. The other options are distractors describing related-but-distinct ideas: general 'ease of use and aesthetics' (too vague, not the ISO definition), 'methodology for profit' (conflates usability with business ROI), and 'accessibility for challenged users' (accessibility is a related but separate discipline from usability). Only the first option matches the standard's precise wording.