To answer this question, the user needs to know what an index is and how it works.

An index is a data structure that improves the speed of data retrieval operations on a database table. It does this by providing a quick lookup mechanism for finding rows that match certain column values in the table. Indexes are most useful when searching large tables for a specific value or set of values.

Now, let's go through each option and explain why it is right or wrong:

A. The indexed column is declared as NOT NULL: This option is not necessarily the most useful scenario for an index. Declaring a column as NOT NULL simply means that the column cannot contain NULL values. While this may improve data integrity, it does not necessarily make an index more useful.

B. The indexed columns are used in the FROM clause: This option is not necessarily the most useful scenario for an index, either. Using indexed columns in the FROM clause can help improve query performance by allowing the database to retrieve only the necessary rows. However, it does not necessarily make the index more useful than other scenarios.

C. The indexed columns are part of an expression: This option can be useful for an index. When indexed columns are part of an expression, the database can still use the index to search for values that match the expression. This can help improve query performance.

D. The indexed column contains a wide range of values: This option is the most useful scenario for an index. When a column contains a wide range of values, it can be difficult for the database to search through all the values to find the ones that match a specific criteria. However, if the column is indexed, the database can use the index to quickly find the values that match the criteria, which can greatly improve query performance.

Therefore, the correct answer is:

The Answer is: D