Kunti (Kundhi) warned Karna not to use the Nagastra more than once against Arjuna during the Kurukshetra War. The Nagastra was a divine celestial weapon given to Karna by his father, Surya (the sun god), but it could only be used once effectively. Kunti knew that if Karna used it and missed, he would not get another chance to kill Arjuna with this powerful weapon. Krishna, Indra, and Shakuni (Saguni) were not the ones who gave this specific warning.