Tag: biology

Regulator gene regulates the expression of structural genes by its protein products that are mostly transcription factors. These transcription factors bind to the operator region which is located just upstream the binding site of the RNA polymerase and hence prevent the binding and transcription; option D is correct. Operator is a DNA sequence present between the promoter region and the first coding gene. This operator region serves as repressor protein binding site; option B is wrong. Genes which govern more or less same trait or perform same role are called redundant genes; presence of these genes confers advantage of diluting the effect of point mutation on organisms; option C is wrong. Presence of more than one allele on a genetic locus is called gene polymorphism provided that the allele is present with more than 5% frequency in the population; option A is wrong. 

In genetics, a promoter is a region of DNA that initiates transcription of a particular gene. Promoters are located near the transcription start sites of genes, on the same strand and upstream on the DNA (towards the 5' region of the sense strand).

An operon is a functioning unit of genomic DNA containing a cluster of genes under the control of a single promoter. The genes are transcribed together into an mRNA strand and either translated together in the cytoplasm, or undergo trans-splicing to create monocistronic mRNAs that are translated separately. Regulator gene regulates inhibiting transcription of mRNA.

The gene that codes for any RNA/protein product which does not serve as regulatory protein is known as structural genes. The operator is a DNA sequence present between the promoter region and the first coding gene. The operator region serves as the repressor protein binding site. The promoter is a DNA segment that serves to initiate transcription of a particular gene. They are present upstream near the transcription start sites of genes in between the operator and structural gene. The regulatory gene regulates the expression of structural genes by its protein products that are mostly transcription factors. It is not the part of an operon, which means that it is present upstream or downstream the structural genes but not in between; the Regulatory gene is present upstream the operator gene. Thus, the correct answer option D.

In the operon model, the operator is the gene segment to which a repressor binds. This prevents the RNA polymerase from transcribing certain genes in the operon unit.

Lac repressor is part of the regulatory network of the lac operon. Lac repressor controls the production of three proteins produced from the gene and affecting the metabolism of lactose. This repressor molecule is a tetramer whose all the subunits are identical. This tetramer binds to a particular region in the bacterial DNA called the operator. This region is present next the three lactose metabolizing proteins. Binding of the repressor to operator causes the block in the production of protein. Otherwise, for three genes to transcribe the repressor protein binds to the lactose molecule and hence unable to bind to operator allows the genes to transcribe.