Tag: oxidative phosphorylation

Reduced molecules like NADH+H+ and FADH2 yield energy in the form of ATP when they undergo ETC in mitochondria. NADH+H+ enter ETC at higher complex than FADH2 so they release energy as 3 ATP and 2 ATP respectively.

The Krebs cycle is the condensation of acetyl group with oxaloacetic acid and water to yield citric acid and leads to the formation of Oxalo acetic acid.

Phosphorylation is the addition of a phosphate (PO$ _{4}^{3-}$) group to a protein or other organic molecule. Phosphorylation results in the formation of ATP, which is the energy currency of cell. Phosphorylation occurs as a part of glycolysis, Kreb's cycle and HMP pathway.

Oxidative phosphorylation is a metabolic process, which is a part of respiration, which occurs in mitochondria. As a result of this process energy is released in the form of ATP.

Oxidative phosphorylation refers to synthesis of ATP by ADP and Pi driven by energy released from oxidation of reducing powers NADH and FADH2 by transfer of their electrons through electron trasnport chain to oxygen. Electron trasnport chain is present in inner mitochondrial membrane and passes the electrons down a series of carriers and pump protons into the intermembrane space. Oxygen serves as final electron acceptor in oxidation of NADH and FADH2 and the resulting proton gradient serves as energy source for the enzyme ATP synthase to synthesize ATP. So final products of oxidative phosphorylation are ATP, NAD and FAD. DPN (diphosphopyridine nucleotide), also called as NAD. Correct answers are D and B. NADP is coenzyme of photosynthetic light reactions. Puruvic acid is product of glycolysis. 

Oxidative phosphorylation is the metabolic pathway in which the mitochondria in cells use their structure, enzymes and energy released by the oxidation of nutrients to reform ATP in respiration.

Biological phosphorylation is of two types- protein phosphorylation and oxidative phosphorylation. In protein phosphorylation, the proteins get attached with a phosphate group. Oxidative phosphorylation is the metabolic pathway in which the mitochondria in cells use their structure, enzymes, and energy released by the oxidation of nutrients to reform ATP.

During one of the steps of Krebs cycle, succinic acid is converted to fumaric acid. The reaction is accompanied by coenzyme FAD (flavin adenine nucleotide). This oxidation reaction liberates less free energy as compared to other oxidation reactions. FAD$^+$ is the hydrogen acceptor in this reaction as there is very less free-energy change. In this reaction, succinic acid is oxidized to fumaric acid. At the same time, FAD$^+$ is reduced to FADH$ _2$. 

The electrons from NADH AND FADH$ _2$ flows through the inner mitochondrial membrane, thus forming a proton gradient i.e; building an H+ pump which flows through the membrane enzyme complex. An enzyme responsible for this process and energy generation is ATP synthase.