Multiple choice botany nucleus and chromosome membrane bound organelles cell: size and differentiation microscopy Which chromosome may be lost during cell division? Giant chromosome Acentric chromosome Polycentric chromosome Telocentric chromosome Reveal answer Fill a bubble to check yourself B Correct answer Explanation Acentric chromosome may lost during cell division as centromere is absent in them. During metaphase and anaphase spindle fibres are not attached with them and so they are not able to reach to the poles.