Tag: transgenic animals

Questions Related to transgenic animals

Which of the following is the ethics for the research with animals?

  1. Surgical procedure under appropriate anesthesia

  2. Research with professional standard

  3. Any animal can be used

  4. Both A and B


Correct Option: D
Explanation:
Anesthesia enables a animals to tolerate surgical procedures that would otherwise inflict unbearable pain.
Bioscience community accepts that animals should be used for research only within an ethical framework.

Animal suffering during testing can be minimized by which of these principles of ethics of animal biotechnology?

  1. Reduction

  2. Refinement

  3. Replacement

  4. All of the above


Correct Option: B
Explanation:

Refinement refers to methods that minimise the pain, suffering, distress or lasting harm that may be experienced by research animals, and which improve their welfare. 

Refinement applies to all aspects of animal use, from their housing and husbandry to the scientific procedures performed on them.

All of the followings are the ethical issues with the animal testing except

  1. Pain

  2. Disease

  3. Infertility

  4. All of the above


Correct Option: C
Explanation:

Pain and disease are major ethical issues. Infertility is not one of them.

The transgenic animals are those which have 

  1. Foreign DNA in some of its cells

  2. Foreign DNA in all its cells

  3. Foreign DNA and RNA in some of its cells

  4. Foreign DNA and RNA in all its cells


Correct Option: B
Explanation:
Transgenic animals are animals that have had a foreign gene deliberately inserted into their genome. Such animals are most commonly created by the micro-injection of DNA into the pronuclei of a fertilised egg which is subsequently implanted into the oviduct of a  surrogate mother.
So, the correct answer is 'Foreign DNA in all its cells'

Mule is a product of

  1. Breeding

  2. Mutation

  3. Hybridisation

  4. Interspecific hybridisation


Correct Option: D
Explanation:

An interspecific hybrid is the product of mating between parents of two different species. A mule is the offspring of a male donkey and a female horse (mare). Mules are more patient, sure-footed, hardy and long-lived than horses, and they are considered less obstinate, faster, and more intelligent than donkeys.

So, the correct answer is 'Interspecific hybridisation'

Genetic engineering has been successfully used for producing
  1. transgenic mice for testing safety of polio vaccine before use in humans

  2. transgenic models for studying new treatments for certain cardiac disease

  3. transgenic Cow-Rosie which produces high fat milk for making ghee

  4. Animals like bulls for farm work as they have super power


Correct Option: A
Explanation:

In research studies, animals that have been genetically engineered include cattle, pigs, chickens, goats, sheep, dogs, cats, fish, rats and mice. As scientists have sequenced the genomes of domestic animals, more is known about genes and the traits that they control.

So, the correct option is 'Transgenic mice for testing the safety of the polio vaccine before use in humans'.

Bioreactors are

  1. Transgenic animals

  2. Fermentation factories

  3. Both (A) and (B)

  4. None of the above


Correct Option: B
Explanation:

A bioreactor may refer to any manufactured or engineered device or system that supports a biologically active environment. In animals, the production of biologically active recombinant proteins use transgenic animals as bioreactor. Bioreactor or fermentation processes are the core manufacturing process in the biotech industry. 

In transgenics, expression of transgene in target tissue is determined by __________.

  1. Enhancer

  2. Transgene

  3. Promoter

  4. Reporter


Correct Option: D

Transgenic animal has

  1. Foreign DNA is all its cells

  2. Foreign RNA is all its cells

  3. Foreign DNA is some of the cells

  4. Both B and C


Correct Option: A
Explanation:

A transgenic animal is one that carries a foreign gene that has been deliberately inserted into its genome. The foreign gene is constructed using recombinant DNA methodology. A transgenic organism carries in all its cells a foreign gene that was inserted by laboratory techniques. Each transgenic organism is produced by introducing cloned genes, composed of deoxyribonucleic acid (DNA) from microbes, animals or plants, into plant and animal cells. 

Thus, the correct answer is option A.

Reporter genes which are used in transformation are of types

  1. Selectable marker gene

  2. Scoreable marker gene

  3. Antibiotic resistant gene

  4. Both A and B


Correct Option: D