Tag: transgenic organisms

Questions Related to transgenic organisms

Which of the following is not a benefit of transgenic animals?

zoology biotechnology and its applications transgenic animals transgenic organisms applications of biotechnology

  1. Investigation of new treatments for diseases

  2. Early detection of diseases

  3. Testing the safety of vaccines

  4. To produce useful biological products

Show answer
Correct Option: B
Explanation:

Early diagnosis of disease cannot be done by transgenic animals but through techniques such as PCR and ELISA.

Inbreeding for five generations led to production of homozygous transgenic mice. However, these homozygous males or females were infertile. Which of the following approaches is most preferable and economical to obtain heterozygous transgenic animals continuously?

zoology biotechnology and its applications transgenic animals transgenic organisms applications of biotechnology

  1. More transgenic founder (1st animal) should be generated.

  2. Crossing (breeding) of transgenic mice with wild type mice in earlier generations should be done for continued production of transgenic heterozygous offsprings

  3. Inbreeding should be avoided after 5th generation

  4. Homozygous transgenic mice should be mated with heterozygous transgenic mice for continued production of transgenic heterozygous offsprings.

Show answer
Correct Option: B
Explanation:

Interbreeding of particular species for a larger amount of time causes the recessive traits to appear in the offspring and those result in infertility. Inbreeding is not recommended and cross-breeding is required. When the transgenic mice are inbred for very large duration infertility is caused.

To get heterozygous transgenic mice crossbreeding should be done with the wild-type.
So, the correct option is 'Crossing (breeding) of transgenic mice with wild type mice in earlier generations should be done for continued production of transgenic heterozygous offsprings'

Select the incorrect matched pair.

zoology biotechnology and its applications transgenic animals transgenic organisms applications of biotechnology

  1. Monoclonal antibodies - Hybridomas

  2. PCR - Phenylketonuria

  3. Bioweapons - Bacillus anthracis

  4. Tracy - First transgenic animal for food production

Show answer
Correct Option: D

A human protein which is obtained from transgenic animals and is used to treat emphysema is 

zoology biotechnology and its applications transgenic animals transgenic organisms applications of biotechnology

  1. Alpha-lactalbumin

  2. Thyroxine

  3. $\alpha-1$-antitrypsin

  4. Insulin.

Show answer
Correct Option: C
Explanation:

A human protein which is obtained from transgenic animals and is used to treat emphysema is α−1-antitrypsin. Transgenic animals that produce useful biological products can be created by the introduction of the portion of DNA which codes for particular product such as human proteins. 

So, the correct option is 'Option C' .

What is ANDi?

zoology biotechnology and its applications transgenic animals transgenic organisms applications of biotechnology

  1. Transgenic cow

  2. Transgenic dog

  3. Transgenic sheep

  4. Transgenic monkey

Show answer
Correct Option: D
Explanation:

ANDi, is the first transgenic monkey. It has been named ANDi, the acronym of "inserted DNA". In this DNA of a fluorescent jellyfish was introduced into an unfertilised egg of a Rhesus monkey in a test tube.

95% of the existing transgenic animals are 

zoology biotechnology and its applications transgenic animals transgenic organisms applications of biotechnology

  1. Fish

  2. Pigs

  3. Sheep

  4. Mice

Show answer
Correct Option: D
Explanation:

Transgenic rats, rabbits, pigs, sheep, cows and fish have been produced, althrough 95% of all existing transgenic animals are mice.

Given below are certain features of mice. Read them and select why mice is most preferred animal for studies on gene transfer.


(i) Short estrous cycle and gestation period
(ii) Relatively short generation time
(iii) Convenient in vitro fertilisation
(iv) Production of several offspring per pregnancy 

zoology biotechnology and its applications transgenic animals transgenic organisms applications of biotechnology

  1. (i) and (ii) only

  2. (i) only

  3. (i), (ii) and (iv) only

  4. (i), (ii), (iii) and (iv)

Show answer
Correct Option: D
Explanation:

Mouse is the most preferred animal for studies on gene transfer due to many favourable features like short oestrous cycle and gestation period, relatively short generation time, production of several offspring per pregnancy, convenient in vitro fertilisation, successful culture of embryo in vitro, etc.

Giant mouse has been produced through

zoology biotechnology and its applications transgenic animals transgenic organisms applications of biotechnology

  1. Gene transfer

  2. Gene differentiation

  3. Tissue culture

  4. All of these

Show answer
Correct Option: A
Explanation:

Transgenic mouse is larger because expression of the gene for human growth factor has been introduced into it.

Read the following statements : 
I) Mule is developed by interspecific hybridisation
II) Groups of bees is called 'swarms'
III) For the herd-improvement cross-breeding is employed
IV) In MOET, fertilised egg at 6-8 celled stage is recovered non - surgically

zoology biotechnology and its applications transgenic animals transgenic organisms applications of biotechnology

  1. I, II, III, IV are true

  2. III , IV, V are false

  3. I, II, IV are true

  4. I, II, III and V are true

Show answer
Correct Option: A
Explanation:

  • As a mule is produced by crossing a female horse with a male donkey, it can be said to be an interspecific hybrid.
  • Swarming can be defined as the process by which a queen bee forms a new colony. Consequently, the term ‘swarms’ is used to refer to the colonies of honey bees.
  • Cross-breeding enables the production of hybrids that are superior in one respect or the other to their respective parents.
  • In MOET, the female is made to produce more eggs than normal, usually 6-8. After the fertilization of these eggs with sperms, these fertilized eggs are non-surgically removed and transferred to other females.
Hence, the correct answer is 'I, II, III, IV are true'.

The injecting of foreign gene in an animal gives rise to 

zoology biotechnology and its applications transgenic animals transgenic organisms applications of biotechnology

  1. Transgenic animal

  2. Transgenic organism

  3. Transgenic plant

  4. Transcribed animal

Show answer
Correct Option: A
Explanation:

Transgenic animals are animals that have had a foreign gene deliberately inserted into their genome. Such, animals are most commonly created by micro-injection of DNA into the pronuclei of a fertilized egg which is implanted into the oviduct of a pseudopregnant surrogate mother. This results in the recipient giving birth to genetically modified offspring.