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Pharmacology and Therapeutics
1,699 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
What is the primary mechanism of ototoxicity caused by methotrexate?
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Interference with neurotransmitter release
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Inhibition of protein synthesis
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Damage to hair cells in the inner ear
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Blockage of ion channels in the cochlea
C
Correct answer
Explanation
Methotrexate primarily causes ototoxicity by damaging the hair cells in the inner ear, which are responsible for hearing and balance. This damage can lead to hearing loss and vestibular dysfunction.
What is the primary mechanism of ototoxicity caused by nevirapine?
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Interference with neurotransmitter release
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Inhibition of protein synthesis
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Damage to hair cells in the inner ear
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Blockage of ion channels in the cochlea
C
Correct answer
Explanation
Nevirapine primarily causes ototoxicity by damaging the hair cells in the inner ear, which are responsible for hearing and balance. This damage can lead to hearing loss and vestibular dysfunction.
Which of the following is a common measure of adherence to medical treatment?
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Pill counts
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Pharmacy refill records
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Electronic medication monitors
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All of the above
D
Correct answer
Explanation
All of the above are common measures of adherence to medical treatment.
What is the term for the use of multiple medications by a single patient?
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Polypharmacy
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Medication non-adherence
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Drug-drug interactions
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Medication allergies
A
Correct answer
Explanation
Polypharmacy refers to the use of multiple medications by a single patient.
What is the term for an adverse event that occurs when two or more medications are taken together?
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Polypharmacy
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Medication non-adherence
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Drug-drug interactions
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Medication allergies
C
Correct answer
Explanation
Drug-drug interactions occur when two or more medications interact with each other, leading to an adverse event.
What is the term for a medication that is prescribed to treat a symptom or condition that is caused by another medication?
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Polypharmacy
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Medication non-adherence
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Drug-drug interactions
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Cascading medication
D
Correct answer
Explanation
Cascading medication refers to a medication that is prescribed to treat a symptom or condition that is caused by another medication.
What is the term for a medication that is prescribed to prevent a disease or condition from occurring?
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Prophylactic medication
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Preventive medication
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Maintenance medication
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All of the above
D
Correct answer
Explanation
Prophylactic medication, preventive medication, and maintenance medication all refer to medications that are prescribed to prevent a disease or condition from occurring.
Which of the following is a common medication-related problem among older adults that can lead to dehydration?
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Diuretics
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Laxatives
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Antidepressants
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All of the above
D
Correct answer
Explanation
Diuretics, laxatives, and antidepressants can all contribute to dehydration among older adults.
What is the term for a medication that is prescribed to treat a specific disease or condition?
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Curative medication
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Therapeutic medication
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Symptom-relief medication
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All of the above
D
Correct answer
Explanation
Curative medication, therapeutic medication, and symptom-relief medication all refer to medications that are prescribed to treat a specific disease or condition.
Which of the following is a common medication-related problem among older adults that can lead to constipation?
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Opioids
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Antidepressants
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Calcium channel blockers
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All of the above
D
Correct answer
Explanation
Opioids, antidepressants, and calcium channel blockers can all contribute to constipation among older adults.
What is the term for a medication that is prescribed to relieve a symptom or condition without curing the underlying disease?
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Symptom-relief medication
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Palliative medication
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Supportive medication
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All of the above
D
Correct answer
Explanation
Symptom-relief medication, palliative medication, and supportive medication all refer to medications that are prescribed to relieve a symptom or condition without curing the underlying disease.
What is the treatment for a rice allergy?
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Avoidance of rice
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Antihistamines
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Epinephrine
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All of the above
D
Correct answer
Explanation
The treatment for a rice allergy includes avoidance of rice, antihistamines, and epinephrine.
What is the first-line treatment for neonatal hyperglycemia?
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Insulin therapy
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Oral hypoglycemic agents
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Dietary modifications
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Intravenous fluids
D
Correct answer
Explanation
Intravenous fluids are the first-line treatment for neonatal hyperglycemia, as they help to dilute the glucose in the blood and promote hydration.
Which of the following is not a common type of adverse drug reaction?
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Allergic reaction
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Side effect
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Overdose
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Withdrawal reaction
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Teratogenic effect
E
Correct answer
Explanation
Teratogenic effects are not a common type of adverse drug reaction, as they typically occur during pregnancy and can cause birth defects.
Which of the following is not a common type of drug interaction?
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Drug-drug interaction
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Drug-food interaction
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Drug-herb interaction
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Drug-alcohol interaction
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Drug-disease interaction
E
Correct answer
Explanation
Drug-disease interactions are not a common type of drug interaction, as they typically occur when a drug interacts with a specific disease or condition.