Chemistry ยท Biology
Pharmacology and Therapeutics
1,643 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
What is the purpose of antihistamines in managing skin allergies?
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Relieving itching
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Reducing inflammation
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Clearing up rashes
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Preventing allergic reactions
A
Correct answer
Explanation
Antihistamines are commonly used to relieve itching associated with skin allergies.
Which of the following is NOT a route of drug administration?
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Oral
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Intravenous
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Inhalation
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Transdermal
D
Correct answer
Explanation
Transdermal is not a route of drug administration, as it refers to the absorption of drugs through the skin.
The process by which a drug moves from its site of administration to its site of action is known as:
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Pharmacokinetics
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Pharmacodynamics
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Metabolism
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Excretion
A
Correct answer
Explanation
Pharmacokinetics is the study of the movement of drugs in the body, including absorption, distribution, metabolism, and excretion.
Which of the following is NOT a mechanism of drug action?
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Receptor binding
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Enzyme inhibition
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Ion channel modulation
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Genetic modification
D
Correct answer
Explanation
Genetic modification is not a mechanism of drug action, as it involves altering the genetic makeup of an organism.
The time it takes for a drug to reach its peak concentration in the blood is known as:
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Onset of action
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Time to peak concentration
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Half-life
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Duration of action
B
Correct answer
Explanation
Time to peak concentration is the time it takes for a drug to reach its highest concentration in the blood after administration.
The process by which a drug is broken down in the body is called:
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Metabolism
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Excretion
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Distribution
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Absorption
A
Correct answer
Explanation
Metabolism is the process by which a drug is broken down into smaller molecules, usually by enzymes in the liver.
The process by which a drug is eliminated from the body is called:
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Metabolism
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Excretion
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Distribution
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Absorption
B
Correct answer
Explanation
Excretion is the process by which a drug is eliminated from the body, usually through the kidneys or liver.
Which of the following is NOT a factor that can affect drug metabolism?
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Age
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Gender
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Genetics
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Disease state
D
Correct answer
Explanation
Disease state is not a factor that can affect drug metabolism, as it is the process by which a drug is broken down in the body.
The dose of a drug that produces a desired therapeutic effect is known as:
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Minimum effective dose
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Maximum tolerated dose
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Therapeutic dose
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Median effective dose
C
Correct answer
Explanation
Therapeutic dose is the dose of a drug that produces a desired therapeutic effect without causing unacceptable side effects.
The dose of a drug that produces toxic effects is known as:
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Minimum effective dose
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Maximum tolerated dose
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Therapeutic dose
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Median effective dose
B
Correct answer
Explanation
Maximum tolerated dose is the highest dose of a drug that can be administered without causing unacceptable side effects.
The difference between the therapeutic dose and the toxic dose of a drug is known as:
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Therapeutic index
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Safety margin
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Efficacy
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Potency
A
Correct answer
Explanation
Therapeutic index is the ratio of the toxic dose to the therapeutic dose of a drug.
Which of the following is NOT a type of drug interaction?
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Synergism
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Antagonism
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Potentiation
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Metabolism
D
Correct answer
Explanation
Metabolism is not a type of drug interaction, as it is the process by which a drug is broken down in the body.
When two drugs produce a combined effect that is greater than the sum of their individual effects, it is known as:
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Synergism
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Antagonism
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Potentiation
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Metabolism
A
Correct answer
Explanation
Synergism is when two drugs produce a combined effect that is greater than the sum of their individual effects.
When two drugs produce a combined effect that is less than the sum of their individual effects, it is known as:
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Synergism
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Antagonism
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Potentiation
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Metabolism
B
Correct answer
Explanation
Antagonism is when two drugs produce a combined effect that is less than the sum of their individual effects.
When one drug increases the effect of another drug, it is known as:
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Synergism
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Antagonism
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Potentiation
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Metabolism
C
Correct answer
Explanation
Potentiation is when one drug increases the effect of another drug.