Biology

Molecular Genetics

917 Questions

Molecular genetics explores the mechanisms of genetic information transfer, including DNA replication, transcription, and translation. It is a core component of biology syllabi. These concepts frequently appear in general science sections of major competitive exams.

DNA replicationTranscription processTranslation processRNA typesCentral dogma

Molecular Genetics Questions

Multiple choice bio-chemistry organization of life concept of metabolism metabolism in animals metabolism

Which of the following life processes is evolved around RNA?

  1. Metabolism

  2. Translation

  3. Splicing

  4. All of these

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

RNA plays a central role in various life processes, including the synthesis of proteins (translation), the processing of pre-mRNA (splicing), and various regulatory metabolic functions. Therefore, all listed processes involve RNA.

Multiple choice botany option b: biotechnology and bioinformatics insertion and ligation of dna cutting, insertion and ligation of dna biotechnology in agriculture

Find the correct statement with respect to function or properties of RNA polymerase.

  1. Bacteria have $3$ different types of RNA polymerase
  2. RNA polymerase binds to promoter and initiate transcription

  3. It uses nucleoside monophosphate as substrate

  4. RNA polymerase polymerizes in a template independent manner

Reveal answer Fill a bubble to check yourself
A Correct answer
Multiple choice zoology molecular basis of inheritance the search for genetic material dna structure and replication molecular genetics

Griffith effect is

  1. DNA transcription

  2. RNA translation

  3. Bacterial transformation

  4. Bacterial transduction

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

The Griffith effect refers to the discovery of bacterial transformation, where non-virulent bacteria were converted into virulent ones by a 'transforming principle' from dead virulent bacteria.

Multiple choice zoology molecular basis of inheritance the search for genetic material dna structure and replication molecular genetics

Correct sequence of code transfer during polypeptide formation is

  1. DNA, mRNA, tRNA and amino acids

  2. DNA, tRNA, rRNA and mRNA

  3. mRNA, tRNA, DNA and amino acids

  4. rRNA, DNA, mRNA and tRNA

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

The central dogma of molecular biology describes the flow of genetic information: DNA is transcribed into mRNA, which is then translated into a polypeptide chain using tRNA and amino acids.

Multiple choice botany mendel's law of inheritance genetics terminology similarities and dissimilarities in organisms introduction to genetics features of human body and sign language

A gene is

  1. Synonym of chromosomes

  2. Composed of mRNA

  3. A specific segment of nucleotides of DNA

  4. Having only those nucleotides required to synthesize a protein

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

A gene is a sequence of nucleotides along a DNA strand - with 'start' and 'stop' codons and other regulatory elements - that specifies a sequence of amino acids that are linked together to form a protein.


So, the correct answer is 'A specific segment of nucleotides of DNA'.

Multiple choice botany option b: biotechnology and bioinformatics dna transfer rdna technology - dna transfer and transformation biotechnology in agriculture

Find the odd one among the following methods of rDNA transfer into host cell.

  1. Biolistics

  2. Gene gun

  3. Microinjection

  4. Retroviral vector

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

There are various methods of making the host cell competent for transformation with Recombinant DNA technology.

Microinjection method is one where the recommended DNA is directly injected into the nucleus of the animal cell. In the gene gun method, the bombardments on plant cell with high-velocity microparticles of gold or tungsten coated with DNA is done which is known as biolistic or gene gun.
The pathogen vectors are allowed to infect the cell and transfer the recombinant DNA into the host cell which is known as the retroviral vector method.
So, the correct option is 'Biolistics'.

Multiple choice biology organization of life comparison of prokaryotic vs eukaryotic cells prokaryotic cell and eukaryotic cell types of cell

Transcription and translation occur in the cytoplasm in a/an

  1. Prokaryotic cell

  2. Eukaryotic cell

  3. Unicellular organism only

  4. None of the above

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Transcription is the process of formation of RNA from DNA. Transcription takes place inside the nucleus, where the DNA of a cell is stored. Since eukaryotes have a defined membrane bound nucleus, therefore transcription always takes place inside the nucleus in eukaryotic cells.
Translation, on the other hand is the process of production of proteins from messenger RNA. Production of proteins require ribosomes and ribosomes are found in cytoplasm. Thus, translation always occurs inside cytoplasm, whether it is a prokaryotic or eukaryotic cell.
In prokaryotes, however there is no define membrane bound nucleus. The DNA or the genetic material of prokaryotes lie inside cytoplasm only. Therefore, prokaryotic cells are the only cells where transcription and translation both occurs inside cytoplasm.
Hence, the correct option 'Prokaryotic cell'.

Multiple choice biology organization of life comparison of prokaryotic vs eukaryotic cells prokaryotic cell and eukaryotic cell types of cell

Assertion:  Initiation step of protein synthesis in prokaryotes and eukaryotes has several differences.

Reason:  They both form mRNA - tRNA complex with smaller subunit of ribosome.

  1. If both the assertion and the reason are true and the reason is a correct explanation of the assertion

  2. If both the assertion and reason are true but the reason is not a correct explanation of the assertion

  3. If the assertion is true but the reason is false

  4. If both the assertion and reason are false

  5. If the assertion is false but reason is true

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

The differences between initiation step of protein synthesis in eukaryotes and prokaryotes are : 

(i) In prokaryotes initiation factors are three - IF1, IF2 and IF3. Eukaryotes have at least ten initiation factors - eIF1, eIF2, elF3, eIF4A, eIF4B, eIF4C, eIF4D, eIF4F, eIF5 and eIF6. 
(ii) In eukaryotes, formylation of methionine does not take place. In prokaryotes tRNA is charged with formylated methionine.
 (iii) The larger subunit of ribosome combines with 40S - mRNA - tRNAMet (in case of prokaryotes, 30S) complex to form intact ribosome. It requires initiation factor IF1 in prokaryotes and factors eIF1, eIF4 (A, B, C) in eukaryotes.

Multiple choice biology concept of life theories of the origin of life origin of life the origin of cells and cell division

The first genes may have developed when

  1. Protobionts grew and divided

  2. Short RNA strands self-replicated

  3. DNA molecules produced RNA molecules

  4. Polypeptides became catalytic

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

RNA is capable of catalyzing a number of chemical reactions, including the polymerization of nucleotides. RNA is uniquely able both to serve as a template for and to catalyze its own replication. Consequently, RNA is generally believed to have been the initial genetic system, and an early stage of chemical evolution is thought to have been based on self-replicating RNA molecules—a period of evolution known as the RNA world.

So the correct option is 'short RNA strands self-replicated'.

Multiple choice commercial studies biotechnology: general introduction introduction to genetic engineering and production of insulin use of efficient and eco-friendly technology genetics of the future

The drug streptomycin inhibits the process of

  1. Prokaryotic translation

  2. Eukaryotic translation

  3. Prokaryotic transcription

  4. Eukaryotic transcription

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation
When purifying protein from a biological extract, streptomycin sulfate is sometimes added as a means of removing nucleic acids. Since it binds to ribosomes and precipitates out of solution, it serves as a method for removing rRNA, mRNA, and even DNA if the extract is from a prokaryote
So, the correct answer is 'Prokaryotic translation'