Biology
Molecular Biology and Genetics
717 Questions
Molecular biology and genetics explore the structure and function of DNA, RNA, genetic mutations, and heredity. Understanding these building blocks of life is essential for most biology examinations. Review these practice questions to test your molecular genetics knowledge.
DNA structure and basesGenetic mutationsNucleic acids compositionDNA sequencing and replication
Molecular Biology and Genetics Questions
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deoxyribose
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base
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ribose
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phosphate group
A
Correct answer
Explanation
RNA contains ribose sugar, not deoxyribose. Deoxyribose is the sugar found in DNA.
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wax
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chemical bonds
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protein
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energy
C
Correct answer
Explanation
DNA provides the genetic instructions for synthesizing proteins. The process involves transcription into RNA and translation into amino acid sequences.
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hydrogen
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ionic
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covalent
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phosphate
A
Correct answer
Explanation
The two strands of the DNA double helix are held together by hydrogen bonds between the complementary nitrogenous bases (A-T and G-C).
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it proofreads and corrects for errors in base pairing
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it is unable to initiate synthesis; requires RNA primer
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it works only in the 5' → 3' direction
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it forms the bond between complementary base pairs
D
Correct answer
Explanation
DNA polymerase adds nucleotides to the growing strand by forming phosphodiester bonds between the 3'-OH of the existing strand and the 5'-phosphate of the incoming nucleotide. It does not form the hydrogen bonds between base pairs; those form spontaneously based on complementarity.
B
Correct answer
Explanation
According to Chargaff's rules, A=T and G=C. If Thymine is 20%, then Adenine is also 20%. The remaining 60% must be split equally between Guanine and Cytosine, so Guanine is 30%.
B
Correct answer
Explanation
Adenine and Guanine are the two purine bases found in DNA.
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Nucleosides
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Nucleotides
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Nucleic acids
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Phosphate groups
B
Correct answer
Explanation
DNA is a polymer made of repeating units called nucleotides, which consist of a sugar, a phosphate, and a nitrogenous base.
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DNA
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Blood cells
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Chromosomes
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Genes
C
Correct answer
Explanation
Chromosomes are long, threadlike structures composed of DNA and proteins that carry genetic information. They are located within the nucleus of eukaryotic cells.
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Dominant Nuclear Acid
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Daily Nursing Applejuice
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Deoxyribonucleic Acid
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Dino Nuggets Arithmetic
C
Correct answer
Explanation
DNA is an acronym for Deoxyribonucleic Acid, which is the molecule that carries the genetic instructions for life.
B
Correct answer
Explanation
RNA is generally less stable than DNA and lacks the extensive proofreading mechanisms that DNA replication possesses, leading to higher mutation rates and faster potential evolution.
B
Correct answer
Explanation
RNA is more susceptible to mutation because it is single-stranded and lacks the robust error-correction machinery that double-stranded DNA uses during replication.
A
Correct answer
Explanation
In the structure of DNA, the nitrogenous base cytosine (C) always forms a hydrogen bond with guanine (G) according to Chargaff's rules.
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Crick and Watson’s ladder
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Chutes and Ladders
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genetic code
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double helix
D
Correct answer
Explanation
The double helix is the term used to describe the physical structure of the DNA molecule, which consists of two strands that wind around each other.
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allele
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gene
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chromosome
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double helix
D
Correct answer
Explanation
The double helix is the term used to describe the twisted ladder or spiral staircase structure of the DNA molecule. The other options refer to genetic components or structures, not the shape of the molecule.
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allele
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traits
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chromosome
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double helix
C
Correct answer
Explanation
Chromosomes are threadlike structures made of DNA and proteins that are found in the nucleus of cells. DNA is coiled tightly around proteins to form these structures.