Biology
Endocrine and Metabolic Disorders
617 Questions
Endocrine and metabolic disorders focus on diseases caused by hormonal imbalances, such as goitre, diabetes mellitus, and hyperthyroidism. Test takers will find questions related to disease causes, diagnostic tests like Cushing's syndrome indicators, and clinical treatments. This is a crucial biology topic frequently asked in medical entrance and public service commission examinations.
Thyroid gland disordersGoitre causesDiabetes mellitus characteristicsHyperthyroidism treatmentsGrowth hormone deficiency
Endocrine and Metabolic Disorders Questions
What is the most common cause of Cushing's syndrome in older adults?
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Adrenal tumor
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Pituitary tumor
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Ectopic ACTH production
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Medications
B
Correct answer
Explanation
Pituitary tumor is the most common cause of Cushing's syndrome in older adults, accounting for approximately 70% of cases.
What is the most common cause of growth hormone deficiency in older adults?
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Pituitary tumor
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Head injury
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Radiation therapy
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Medications
A
Correct answer
Explanation
Pituitary tumor is the most common cause of growth hormone deficiency in older adults, accounting for approximately 70% of cases.
What is the most common cause of diabetes insipidus in older adults?
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Head injury
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Pituitary tumor
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Kidney disease
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Medications
A
Correct answer
Explanation
Head injury is the most common cause of diabetes insipidus in older adults, accounting for approximately 50% of cases.
Which of the following is a common geriatric condition characterized by excessive thirst and urination?
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Diabetes insipidus
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Diabetes mellitus
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Polyuria
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Nocturia
A
Correct answer
Explanation
Diabetes insipidus is a common geriatric condition characterized by excessive thirst and urination.
Which of the following is a common complication of type 1 diabetes in children?
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Diabetic ketoacidosis
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Hypoglycemia
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Retinopathy
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All of the above
D
Correct answer
Explanation
Diabetic ketoacidosis, hypoglycemia, and retinopathy are all common complications of type 1 diabetes in children.
What is the primary cause of Addison's disease?
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Autoimmune disorder
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Tuberculosis
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HIV/AIDS
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Cancer
A
Correct answer
Explanation
In Addison's disease, the body's immune system mistakenly attacks and destroys the adrenal glands, leading to a deficiency of hormones produced by these glands.
Which of the following is a potential complication of untreated Addison's disease?
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Addisonian crisis
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Cushing's syndrome
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Grave's disease
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Hyperthyroidism
A
Correct answer
Explanation
Addisonian crisis is a life-threatening complication of untreated Addison's disease, characterized by a severe drop in blood pressure, dehydration, and electrolyte imbalance.
Which of the following is a potential side effect of hormone replacement therapy for Addison's disease?
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Weight gain
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Increased blood pressure
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Muscle weakness
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Mood swings
A
Correct answer
Explanation
Weight gain is a potential side effect of hormone replacement therapy for Addison's disease, as the synthetic hormones can sometimes lead to fluid retention and increased appetite.
What is the recommended dietary modification for individuals with Addison's disease?
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Low-sodium diet
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High-potassium diet
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Low-carbohydrate diet
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High-protein diet
Correct answer
Explanation
Individuals with Addison's disease are recommended to follow a high-sodium diet, as the deficiency of aldosterone can lead to sodium loss and dehydration.
Which of the following is a potential trigger for an Addisonian crisis?
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Physical stress
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Emotional stress
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Infection
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All of the above
D
Correct answer
Explanation
Physical stress, emotional stress, and infection can all be potential triggers for an Addisonian crisis, as these factors can increase the body's demand for cortisol and aldosterone.
Which of the following is a potential long-term complication of untreated Addison's disease?
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Heart disease
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Stroke
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Kidney failure
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All of the above
D
Correct answer
Explanation
Untreated Addison's disease can lead to a number of long-term complications, including heart disease, stroke, and kidney failure, due to the chronic deficiency of cortisol and aldosterone.
What is the recommended dosage of hydrocortisone for individuals with Addison's disease?
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5-10 mg per day
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15-20 mg per day
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25-30 mg per day
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35-40 mg per day
B
Correct answer
Explanation
The recommended dosage of hydrocortisone for individuals with Addison's disease typically ranges from 15 to 20 mg per day, although the exact dosage may vary depending on individual needs and response to treatment.
What is the recommended dietary modification for individuals with Addison's disease who experience low blood pressure?
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Increase sodium intake
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Decrease potassium intake
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Increase fluid intake
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All of the above
D
Correct answer
Explanation
Individuals with Addison's disease who experience low blood pressure are recommended to increase sodium intake, decrease potassium intake, and increase fluid intake to help manage their blood pressure.
Which hormone is commonly used to treat hypothyroidism, a condition characterized by insufficient thyroid hormone production?
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Epinephrine
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Levothyroxine
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Hydrocortisone
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Testosterone
B
Correct answer
Explanation
Levothyroxine is a synthetic form of thyroid hormone that is used to treat hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormone.
Which medication is commonly used to treat hyperthyroidism, a condition characterized by excessive thyroid hormone production?
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Levothyroxine
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Propylthiouracil
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Methimazole
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Liothyronine
B
Correct answer
Explanation
Propylthiouracil is a medication used to treat hyperthyroidism by inhibiting thyroid hormone production.