Biology
Cellular Respiration and Enzymes
1,721 Questions
Explore key concepts of cellular respiration, including glycolysis, the Krebs cycle, and the electron transport chain. These questions also cover ATP production, anaerobic respiration, and essential metabolic pathways. This topic forms a core part of the biology syllabus for many competitive examinations.
Glycolysis and metabolic pathwaysKrebs cycle processesElectron transport chainATP production countAnaerobic respiration products
Cellular Respiration and Enzymes Questions
Which enzyme complex is responsible for the majority of the reactions in the beta-oxidation pathway?
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Pyruvate dehydrogenase complex
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Citrate synthase
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Fatty acid synthase
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Electron transport chain
C
Correct answer
Explanation
Fatty acid synthase is the enzyme complex that catalyzes the majority of the reactions in the beta-oxidation pathway, including the dehydrogenation, hydration, and cleavage steps.
What is the name of the enzyme that catalyzes the dehydrogenation step in the beta-oxidation pathway?
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Acyl-CoA dehydrogenase
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Enoyl-CoA hydratase
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3-Hydroxyacyl-CoA dehydrogenase
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Thiolase
A
Correct answer
Explanation
Acyl-CoA dehydrogenase is the enzyme responsible for catalyzing the dehydrogenation step in the beta-oxidation pathway, converting acyl-CoA to enoyl-CoA.
Which coenzyme is required for the dehydrogenation step in the beta-oxidation pathway?
B
Correct answer
Explanation
FAD (flavin adenine dinucleotide) is the coenzyme required for the dehydrogenation step in the beta-oxidation pathway, accepting electrons from acyl-CoA and transferring them to the electron transport chain.
What is the name of the enzyme that catalyzes the hydration step in the beta-oxidation pathway?
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Enoyl-CoA hydratase
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3-Hydroxyacyl-CoA dehydrogenase
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Thiolase
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Citrate synthase
A
Correct answer
Explanation
Enoyl-CoA hydratase is the enzyme responsible for catalyzing the hydration step in the beta-oxidation pathway, adding a water molecule to enoyl-CoA to form 3-hydroxyacyl-CoA.
Which coenzyme is required for the hydration step in the beta-oxidation pathway?
D
Correct answer
Explanation
Water is the coenzyme required for the hydration step in the beta-oxidation pathway, adding a hydroxyl group to the double bond of enoyl-CoA.
What is the name of the enzyme that catalyzes the cleavage step in the beta-oxidation pathway?
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Thiolase
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Acyl-CoA dehydrogenase
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Enoyl-CoA hydratase
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3-Hydroxyacyl-CoA dehydrogenase
A
Correct answer
Explanation
Thiolase is the enzyme responsible for catalyzing the cleavage step in the beta-oxidation pathway, breaking down 3-hydroxyacyl-CoA into acetyl-CoA and a new acyl-CoA molecule.
What is the name of the metabolic pathway that converts acetyl-CoA derived from fatty acid oxidation into glucose?
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Glycolysis
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Gluconeogenesis
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Glycogenesis
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Krebs cycle
B
Correct answer
Explanation
Gluconeogenesis is the metabolic pathway that converts acetyl-CoA derived from fatty acid oxidation into glucose, allowing the body to produce glucose from non-carbohydrate sources.
Which enzyme catalyzes the rate-limiting step in de novo purine biosynthesis?
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Phosphoribosyl pyrophosphate amidotransferase (PPAT)
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Glutamine phosphoribosyl pyrophosphate amidotransferase (GPAT)
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Inosine monophosphate dehydrogenase (IMPDH)
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Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
A
Correct answer
Explanation
PPAT catalyzes the first step in de novo purine biosynthesis, which is the conversion of phosphoribosyl pyrophosphate (PRPP) to 5-phosphoribosyl-1-amine (PRA).
Which enzyme catalyzes the conversion of IMP to adenosine monophosphate (AMP) and guanosine monophosphate (GMP)?
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Adenylosuccinate synthetase
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Adenylosuccinate lyase
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Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
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Inosine monophosphate dehydrogenase (IMPDH)
A
Correct answer
Explanation
Adenylosuccinate synthetase catalyzes the conversion of IMP to adenylosuccinate, which is then converted to AMP by adenylosuccinate lyase.
What is the final step in the de novo synthesis of purines?
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Conversion of IMP to AMP and GMP
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Conversion of PRA to GAR
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Conversion of SAICAR to AICAR
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Conversion of AICAR to IMP
A
Correct answer
Explanation
The final step in de novo purine synthesis is the conversion of IMP to AMP and GMP by adenylosuccinate synthetase and adenylosuccinate lyase.
Which enzyme catalyzes the conversion of hypoxanthine to xanthine?
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Xanthine oxidase
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Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
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Inosine monophosphate dehydrogenase (IMPDH)
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Adenylosuccinate synthetase
A
Correct answer
Explanation
Xanthine oxidase catalyzes the conversion of hypoxanthine to xanthine, which is then converted to uric acid by uricase.
What is the final product of purine degradation?
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Hypoxanthine
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Xanthine
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Uric acid
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Allantoin
C
Correct answer
Explanation
Uric acid is the final product of purine degradation in humans and other primates.
Which enzyme catalyzes the conversion of xanthine to uric acid?
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Xanthine oxidase
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Uricase
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Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
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Inosine monophosphate dehydrogenase (IMPDH)
B
Correct answer
Explanation
Uricase catalyzes the conversion of xanthine to uric acid.
What is the name of the enzyme that catalyzes the hydrolysis of adenosine to adenine and ribose-1-phosphate?
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Adenosine deaminase
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Adenosine kinase
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Adenosine phosphorylase
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Adenosine synthase
A
Correct answer
Explanation
Adenosine deaminase catalyzes the hydrolysis of adenosine to adenine and ribose-1-phosphate.
Which enzyme catalyzes the conversion of guanine to xanthine?
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Guanine deaminase
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Guanine kinase
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Guanine phosphorylase
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Guanine synthase
A
Correct answer
Explanation
Guanine deaminase catalyzes the conversion of guanine to xanthine.