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Purine Metabolism: Exploring the Pathways for Synthesizing and Degrading Purines

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Multiple Choice

Which enzyme catalyzes the rate-limiting step in de novo purine biosynthesis?

  1. Phosphoribosyl pyrophosphate amidotransferase (PPAT)
  2. Glutamine phosphoribosyl pyrophosphate amidotransferase (GPAT)
  3. Inosine monophosphate dehydrogenase (IMPDH)
  4. Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
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