Human Physiology: Nervous System and Metabolism
Test your knowledge of nervous system physiology, sensory pathways, neural development, and calcium/phosphate metabolism for medical aspirants.
Questions
Which of the following statements regarding the development of the nervous system in humans is not true?
- The neural crest gives rise to the dorsal root ganglia.
- The nervous system develops with the formation of the neural plate.
- The folding of the neural tube forms the mature central nervous system (CNS).
- The CSF is formed continuously by the choroid plexus.
- Neurogenesis stops after complete fetus development.
What is Enteric nervous system?
- It is a complicated assimilate network of neurons in the wall of the gut.
- It is controlled by the CNS
- It is made up of Meissner's and Auerbach's plexuses.
- It regulates the local activity of the gut.
- The enteric nervous system develops from neural crest.
A 43-year-old lady has some facial weakness, a poor cough and weakness of the arms and legs with no reflexes and a loss of feeling to light touch and pin-prick to the wrist and ankle. She must be suffering from
- motor neurone disease
- Guillain Barre syndrome
- spinal cord compression
- myasthenia gravis
- Campylobacter jejuni
Which of the following sensory pathways carries light touch and proprioception?
- Medial lemniscus
- Lateral lemniscus
- Spinothalamic tract
- Chorda tympani
- Corticospinal tract
Damage to which structure may cause a deficit in memory?
- Basal nucleus of Meynert
- Substantia nigra
- Mammillary bodies
- Subthalamic nucleus
- Right posterior parietal cortex
Which of the following statements regarding nerve conduction and synaptic integration is incorrect?
- The synaptic inputs are then associated with the postsynaptic cell.
- The action potential on entering the synapse causes the release of neurotransmitters.
- The binding of neurotransmitters with the pre and post synaptic membranes cause the change in membrane potential.
- In myelinated neurons, the action potential acts at node of Ranvier .
- Neurotransmitters gets activated at the synaptic junction.
Which of the following does not characterise the blood supply of the central nervous system?
- The vertebrobasilar system which constitutes the anterior circulation.
- At the core of the brain, the arteries form the circle of Willis.
- Abnormalities of blood flow in the carotid arteries frequently leads to the problems in the cerebral hemisphere .
- Abnormalities of blood flow in the vertebral arteries frequently leads to the defects in brainstem, cerebellum and posterior parts of the brain.
- Thrombus and emboli are the chief causes of blood flow obstructions in the brain.
Which of the following statements is incorrect regarding the regulation of calcium and phosphate?
- Parathyroid hormone stimulates osteoblasts.
- Vitamin D increases calcium absorption from the gut .
- Parathyroid hormone promotes phosphate excretion.
- Parathyroid hormone is released when there is fall in ionised calcium in the blood.
- Parathyroid hormone decelerates vitamin D production in the kidney.
Select the incorrect statement regarding the spinal cord.
- Sensory information on pain and temperature is delivered by the spinothalamic system .
- Sensory information is transmitted up the dorsal column system.
- The corticospinal tract is mainly implicated with regular distal motor control.
- The cervical spinal cord stimulates the arms.
- The spinal cord is highly organized with decending sensory pathways.
Which of the following thalamic nuclei is most associated with the visual system?
- LGN nucleus
- MGN nucleus
- VAN nucleus
- MD nucleus
- VPL nucleus
Which among the following does not characterise metabolic acidosis?
- In metabolic acidosis, pH is low.
- The anion gap is the calculated difference between the measured cations and the measured anions .
- An increased anion gap metabolic acidosis indicates the accumulation ketoacids or lactic acid.
- To maintain electroneutrality , the level of cations must be decreased.
- A normal anion gap metabolic acidosis indicates loss of bicarbonate.
Which of the following can cause of hypercalcemia in an individual?
- Primary hyperparathryoidism
- Secondary hyperparathyroidism
- Hypovitaminosis of vitamin D
- Chovstek's syndrome
- Acute pancreatitis
Aditi is a patient with substantial plasma hyperphosphatemia. Which of the following may not be true in her case?
- The most likely cause is renal impairment.
- Reduction of dietary intake of phosphate may be helpful in renal failure condition.
- Soft tissue calcification may occur.
- Cell lysis is a possible cause.
- Dialysis cannot remove phosphate and is of no benefit.