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Pyrimidine Metabolism: Investigating the Pathways for Synthesizing and Degrading Pyrimidines
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The initial step in the de novo synthesis of pyrimidines is the formation of:
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A
Orotic acid
💡 Explanation:
The de novo synthesis of pyrimidines begins with the formation of orotic acid from carbamoyl phosphate and aspartate, catalyzed by the enzyme carbamoyl phosphate synthetase II.