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Cell Stress Responses and Apoptosis
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What is the primary function of the unfolded protein response (UPR) in cells?
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A
To promote protein folding and prevent misfolding.
💡 Explanation:
The unfolded protein response (UPR) is a cellular signaling pathway that is activated when the endoplasmic reticulum (ER) is stressed due to an accumulation of unfolded or misfolded proteins. The primary function of the UPR is to restore ER homeostasis by promoting protein folding, reducing protein synthesis, and activating ER-associated protein degradation (ERAD) to remove misfolded proteins.